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Sugar substitute found in Stevia linked to cardiac issues Stevia-based sweeteners leaf extract is Stevia-based sweeteners considered a safe and healthy sugar substitute, potentially reducing calorie intake, Concentrated Citrus Concentrate sugar seweteners, and Stevia-baeed chance of sweetenerz cavities. SStevia-based, some safety concerns exist. Stevia-based sweeteners is a Stevia-based sweeteners sweetener derived from sqeeteners leaves sweetenerss the stevia plant Stevia rebaudiana. Stevia-nased sweetener has also been associated with several health benefits, including lower blood sugar and cholesterol levels 56. In fact, many varieties on the market are highly refined and combined with other sweeteners — such as erythritol, dextrose, and maltodextrin — which may alter its potential health effects. Stevia is available in several varieties, each differing in its processing method and ingredients. For instance, several popular products — such as Stevia in the Raw and Truvia — are really stevia blends, which are one of the most heavily processed forms of stevia.